NMR LipoProfile® Blood Test



Lipid panel for those concerned about coronary heart disease prevention



This blood test is ordered from Life Extension®. Their doctors prepare the test requests for you to take to a LabCorp location outside of Maryland for your blood draw. The test results go directly to you rather than to your doctor. Results are received quickly and the process is fairly smooth! The cost of this test is not going to be covered by insurance but submission to your FSA/HSA account is possible (not guaranteed). It might just be a PITA to try.

From Life Extension®:
LDL, HDL and triglyceride testing only tells part of the story when it comes to heart disease risk. The NMR LipoProfile® test provides these standard lipid tests along with LDL and HDL particle values, plus risk assessment for insulin resistance. Using state of the art technology known as nuclear magnetic resonance (NMR) spectroscopy, the NMR LipoProfile® is an advanced cholesterol test used to identify people at risk for lipid-related coronary heart disease (CHD).
This panel contains the following tests:
  • LDL particle number (LDL-P)
  • Small LDL particle number (small LDL-P)
  • HDL particle number (HDL-P)
  • LDL particle size
  • A standard cholesterol test (LDL-C, HDL-C, triglycerides and total cholesterol)
  • LP-IR

Sample Report from Life Extension

LDL and HDL particles are the containers that transport cholesterol through your blood stream which can contribute to, or protect against atherosclerosis. Since LDL particles interact with the arterial wall as the beginning of the oxidation process that forms plaque, the higher number of LDL-P and small LDL-P, the greater the risk for CHD.

On the other hand, a higher number of HDL-P is considered to be more protective, since HDL removes LDL by transporting it to the liver. In general, people with higher levels of HDL-P are at a lower risk for CHD. It is also well known that LDL particle size provides extremely important information on cardiovascular health. Small, dense LDL particles are dangerous since they contribute to plaque formation in the arterial wall. Ideally, one would want their results to show large, buoyant LDL particles. Small, dense particles are also closely associated with insulin resistance and an increased risk of developing type 2 diabetes. In addition to the particle size, the NMR LipoProfile® provides a laboratory developed index called LP-IR, with a higher number increasing the probability of developing insulin resistance.

Unfortunately, these vitally important markers contained in the NMR LipoProfile® are not included in the typical cholesterol test from your doctor. Standard lipid profiles utilize inferior technology and are limited to the use of cholesterol as a surrogate marker for your extremely important LDL particle number.

Why use outdated technology when the NMR® LipoProfile can more accurately identify if you are really at risk for insulin resistance and CHD?

Instructions: A 12-14 hour fast is required for this blood test. However, drink plenty of water and take your medications as prescribed.


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